LLM Agent Memory Architecture Design
Design an LLM agent memory architecture that generalizes
Scientific Discovery Agent Harness Design
Redesign a ReAct harness for long-horizon scientific discovery in unseen simulated worlds
Small-Model Math Reasoning Post-Training
Design a distillation recipe for a 1.7B student using a fixed 8B teacher
Vision-Language Compositional Generalization Post-Training
Design a GRPO recipe for visual counting across unseen attribute combinations and renderers
Lean 4 Proof-Search LLM agent Workflow Design
Design a compiler-guided LLM workflow for unseen theorems under fixed inference and checking budgets
Video Point-Track Candidate Routing
Select candidate trajectories and predict visibility under a four-switch budget on unseen videos
TriFinger Cube-Pushing Offline RL
Train a control policy from fixed logged trajectories without simulator interaction
Multi-View Point Cloud Fusion
Fuse noisy multi-view observations into one point cloud
10M-Scale Metadata-Filtered ANN Search
Optimize single-core top-10 vector retrieval under one- and two-tag predicates
EDA Standard-Cell Gate Sizing Optimization
Minimize leakage while satisfying timing, slew, and capacitance constraints on unseen netlists
EDA Flip-Flop Banking and Placement Optimization
Optimize multi-bit flip-flop grouping and legal placement across power, area, timing, and displacement costs
Quantum Color-Code Decoder
Reimplement a colour-code decoder without the usual libraries
Quantum Circuit TDD Contraction Planning
Choose contraction pairs to minimize peak diagram size and runtime in exact equivalence checking
Ragged GQA Training Kernel Optimization
Accelerate packed variable-length attention with complete Q/K/V backward passes on unseen shapes
Multi-Stream Gated FlashFFTConv Kernel Optimization
Accelerate gated causal long convolutions across independent streams and unseen shapes
Paged Ragged GQA Decode Kernel Optimization
Accelerate grouped-query attention over paged, variable-length KV caches and unseen shapes
TPU v6e Masked GQA Kernel Optimization
Accelerate decode, prefill, and encoder attention across masks, head-sharing ratios, and unseen shapes
Robot Routing and Macro-Program Optimization
Jointly plan pickup routes and reusable macro recordings to minimize controller button presses
Power-Diode Extreme-Regime I–V Extrapolation
Predict leakage and conduction currents at destructive voltage-temperature conditions from safe-window measurements
Distribution Feeder Model Calibration from Smart-Meter Data
Jointly infer customer phases, line impedances, and regulator taps on unseen feeders
Tidal Seabed Friction Field Inversion
Recover a spatial drag field from sparse, noisy tide-gauge amplitudes and phases on unseen basins
2048 Search-Policy Optimization
Maximize mean game score on unseen seeds under a pooled CPU budget
Query-Budgeted Noisy Black-Box Optimization
Minimize 10-dimensional multimodal objectives with 120 noisy evaluations on unseen instances
Query-Budgeted Stochastic Inventory Policy Optimization
Minimize simulated inventory cost by tuning four replenishment controls within 48 noisy queries
City-Scale Traffic Signal Control Optimization
Coordinate phases, green times, and offsets across ~600 junctions under unseen traffic demand
Fixed-Color-Budget Graph Coloring Optimization
Minimize monochromatic edges on unseen hard graphs under a 45-second solve limit
Defect-Aware Guillotine Glass Cutting Optimization
Pack glass orders into minimum stock plates under staged cuts, defects, and stack-sequence constraints
Cross-Site Chest X-Ray Triage Policy Optimization
Calibrate and rank frozen model scores to prioritize critical studies under a shared review budget
Unsupervised PBMC scATAC Batch Integration
Remove batch effects while preserving cell-type structure in embeddings recomputed on unseen cells
Perturbation-Conditioned Six-Channel Cell Morphology Generation
Generate treated-cell image distributions from controls and condition embeddings without paired examples
Five-Shot Lung scRNA-seq Cell-Type Annotation
Label donor-disjoint cells using five examples per class, an unlabeled pool, and a fixed reference model
Protein–Ligand Co-Folding Inference Optimization
Improve sampling, pose selection, and post-processing under physical-validity and 2 Å RMSD checks
Equity DCF Value-Driver Forecasting
Forecast growth, margins, reinvestment, WACC, and terminal growth for unseen companies from messy fundamentals
Multi-Matter Legal Research and Analysis Agent
Answer regulatory and transactional questions across six matters and 1,000+ case documents
Cross-Sectional Stock Return Ranking
Predict daily forward-return rankings from a 360-factor temporal panel on a sealed later period
Terminal-Task LLM Agent Harness Design
Redesign the harness around a frozen base model for unseen terminal tasks
Mathematical and Statistical Reasoning Workflow Design
Design one LLM workflow for unseen mathematics and statistics problems
Budget-Constrained 3D Gaussian Splat Compression
Compress a 3D Gaussian scene to a fixed primitive budget while preserving novel-view fidelity
Five-Step Diffusion Sampler Schedule Optimization
Optimize a five-evaluation integration schedule for structured image generation
Budget-Constrained Multi-Agent Medical QA Workflow Design
Design a multi-agent workflow for medical question answering under a fixed model-call budget
Point-Track Candidate Lattice Selection and Fusion
Select and fuse candidate trajectories across a point-track lattice
Query-Conditioned Video Evidence Selection Agent Design
Select temporal evidence from candidate tracklets for vision-language question answering
Ten-Evaluation Diffusion Sampler Optimization
Optimize a generative sampler under a fixed ten-evaluation budget
Label-Free World-Model Hallucination Prediction
Predict imminent world-model hallucinations from unlabeled rollout signals
Nuisance-Robust Semantic Image Editing
Preserve a semantic image edit across unseen nuisance transformations
Cross-Language Dart Formatter Reimplementation
Reimplement the Dart source formatter in Haskell with byte-exact output compatibility
PostgreSQL-Compatible Server over SQLite
Implement the PostgreSQL wire protocol in Zig over a SQLite storage engine
EDA Cell Placement, Sizing, and Buffering Optimization
Refine an existing placed netlist to improve power, performance, and area
Mamba-3 Training Kernel Optimization
Optimize Mamba-3 scans with joint states, long ragged sequences, and a full backward pass
Building Indoor-Temperature Extreme Extrapolation
Predict summer indoor temperatures from a single mild-season building record
Climate Subgrid Convection Emulation
Learn a neural parameterization of unresolved convection for a climate model
Dual-Doppler 3D Wind-Field Inversion
Reconstruct three-dimensional wind fields from dual-Doppler radar observations when vertical motion is underdetermined
Online Hybrid-Vehicle Energy Management Policy Optimization
Optimize causal power allocation using only information available to the vehicle online
Exoplanet Transmission-Spectrum Atmospheric Retrieval
Infer atmospheric properties from unseen exoplanet transmission spectra
Sparse-Sensor Damage Mapping
Localize stiffness loss in a steel structure
Fuel-Efficient Real-Time Gear-Shift Policy Optimization
Optimize second-by-second gear selection to reduce fuel use on unseen driving cycles
Molecular HOMO–LUMO Gap Prediction from SMILES
Predict orbital energy gaps for unseen molecules from their SMILES strings
Constrained Ackermann Parking Trajectory Optimization
Plan collision-free parking trajectories for an Ackermann-steered vehicle in tight slots
Photometric Transient and Variable-Source Classification
Classify astronomical transients and variable sources from multiband light curves
Time-Optimal Drone Racing
Fly a quadrotor through gates in minimum time
Suspension Geometry Co-Design
Place suspension hardpoints and pick the tuning that goes with them
Extrapolative Scientific Law Discovery
Discover equation families that extrapolate beyond the observed data rather than only fitting it
Borehole Lithology Sequence Classification
Classify lithology facies along unseen boreholes from multichannel wireline logs
Wake-Aware Wind Farm Layout Optimization
Place turbines to minimize wake losses and maximize energy yield on unseen sites
Query-Budgeted Continuous Black-Box Optimization
Design a self-contained optimizer for unseen 10-dimensional objectives under a 100-evaluation budget
Bilevel Road Capacity and Toll Design
Choose capacity expansions and tolls while accounting for the resulting traffic equilibrium
Self-Financing Rail Network Expansion Planning
Stage rail expansions so operating revenue funds subsequent construction
Time-Windowed Robotaxi Dispatch Optimization
Dispatch a robotaxi fleet for paired pickup and drop-off requests under two-sided time windows
Electric-Van Routing with Charging Detours
Route electric vans while jointly selecting charging detours under battery constraints
Long-Horizon Transport Company Planning Agent
Manage an OpenTTD transport company over a 20-year simulated horizon
Recursive Sokoban Planning Agent
Solve Sokoban instances whose rooms recursively contain other rooms
Large-Scale Pickup-and-Delivery Routing with Time Windows
Route vehicles to serve 500 paired pickup and delivery requests within their time windows
Online Railway Disruption Recovery and Rescheduling
Reschedule trains under unforeseen breakdowns and evolving network availability
Collision-Free Multi-Crane Scheduling
Schedule five terminal cranes that share a rail and cannot pass one another
Real-Time Battle Tetris Planning Agent
Design an agent that survives holds, combos, and incoming garbage under real-time decision constraints
Coverage-Constrained Urban Bus Network Design
Design a bus route network that serves every required node
DNA-to-ATAC Accessibility Prediction
Predict base-resolution chromatin accessibility directly from genomic DNA sequence
12-Lead ECG Chagas Disease Screening
Detect likely Chagas disease cases from unseen 12-lead ECG recordings
Chromatin-to-Gene Expression Prediction
Predict single-cell gene expression from chromatin accessibility profiles alone
Mini-Protein Stability Regression
Train and package a model that predicts stability for unseen mini-protein sequences
Out-of-Distribution Cell Morphology Generation
Generate perturbed-cell morphologies that preserve the requested mechanism of action under distribution shift
Cross-Dataset Single-Cell Label Transfer
Annotate cells across unseen datasets and protocols with a frozen foundation model
Zero-Shot TCR–Epitope Binding Prediction
Score TCR binding to epitopes absent from the training set
Investment Banking Deal-Document Question Answering
Answer transaction and diligence questions grounded in underlying deal files
Management Consulting Engagement-Document Question Answering
Answer consulting questions grounded in underlying engagement files
Arbitrage-Free Implied-Volatility Surface Calibration
Calibrate an arbitrage-free volatility surface from a single noisy market snapshot
Transactional Legal Matter Document Reasoning
Resolve transactional legal matters across a 745-document case corpus
Multivariate Time-Series Structural Break Detection
Detect regime changes across a fleet of noisy time series